TNF-Related Apoptosis-Inducing Ligand: Non-Apoptotic Signalling
Equipe DesCarTes Guerrache A & Micheau O Cells 2024, 13(6), 521; https://doi.org/10.3390/cells13060521 TNF-related apoptosis-inducing ligand (TRAIL or Apo2 or TNFSF10) belongs to the TNF superfamily. When bound to its agonistic receptors, TRAIL can induce apoptosis in tumour cells, while sparing healthy cells. Over the last three decades, this tumour selectivity has prompted many studies aiming at evaluating the … Lire la suite